ENDpoiNTs publications

ENDpoiNTs have published the following articles:

  1. Lupu D, Andersson P, Bornehag CG, et al. The ENDpoiNTs Project: Novel Testing Strategies for Endocrine Disruptors Linked to Developmental Neurotoxicity. Int J Mol Sci. 2020;21(11):3978. doi:10.3390/ijms21113978.
  2. Leemans M, Couderq S, Demeneix B, Fini JB. Pesticides With Potential Thyroid Hormone-Disrupting Effects: A Review of Recent Data. Front Endocrinol (Lausanne). 2019;10:743. doi:10.3389/fendo.2019.00743.
  3. López-Tobón A, Emanuele Villa C, Cheroni C. et al. Human Cortical Organoids Expose a Differential Function of GSK3 on Cortical Neurogenesis. Stem Cell Reports. 2019; 13(5):847-861. doi:
    Demeneix BA. Evidence for Prenatal Exposure to Thyroid Disruptors and Adverse Effects on Brain Development. Eur Thyroid J. 2019;8(6):283-292. doi:10.1159/000504668
  4. Cheroni C, Caporale N, Testa G. Autism spectrum disorder at the crossroad between genes and environment: contributions, convergences, and interactions in ASD developmental pathophysiology. Molecular Autism, accepted for publication
  5. Krebs A, Waldmann T, Wilks MF, Van Vugt-Lussenburg BMA, Van der Burg B, Terron A, Steger-Hartmann T, Ruegg J, Rovida C, Pedersen E, Pallocca G, Luijten M, Leite SB, Kustermann S, Kamp H, Hoeng J, Hewitt P, Herzler M, Hengstler JG, Heinonen T, Hartung T, Hardy B, Gantner F, Fritsche E, Fant K, Ezendam J, Exner T, Dunkern T, Dietrich DR, Coecke S, Busquet F, Braeuning A, Bondarenko O, Bennekou SH, Beilmann M, Leist M. Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data. ALTEX - Alternatives to animal experimentation, 2019;36(4):682-699. doi: 10.14573/altex.1909271.
  6. Karreman, C., Kranaster, P. and Leist, M. SUIKER: Quantification of antigens in cell organelles, neurites and cellular sub-structures by imaging. ALTEX - Alternatives to animal experimentation, 2019; 36(3), pp. 518-520. doi: 10.14573/altex.1906251.
  7. Krebs, A., Nyffeler, J., Karreman, C., Schmidt, B. Z., Kappenberg, F., Mellert, J., Pallocca, G., Pastor, M., Rahnenführer, J. and Leist, M. Determination of benchmark concentrations and their statistical uncertainty for cytotoxicity test data and functional in vitro assays. ALTEX - Alternatives to animal experimentation, 2020; 37(1), pp. 155-163. doi: 10.14573/altex.1912021.
  8. Karreman, C., Klima, S., Holzer, A.-K. and Leist, M. CaFFEE: A program for evaluating time courses of Ca2+ dependent signal changes of complex cells loaded with fluorescent indicator dyes. ALTEX - Alternatives to animal experimentation, 2020; 37(2), pp. 332-336. doi: 10.14573/altex.2003191.
  9. Brüll, M., Spreng, A.-S., Gutbier, S., Loser, D., Krebs, A., Reich, M., Kraushaar, U., Britschgi, M., Patsch, C. and Leist, M. Incorporation of stem cell-derived astrocytes into neuronal organoids to allow neuro-glial interactions in toxicological studies. ALTEX - Alternatives to animal experimentation, 2020; 37(3), pp. 409-428. doi: 10.14573/altex.1911111.
  10. Dreser N, Madjar K, Holzer AK, et al. Development of a neural rosette formation assay (RoFA) to identify neurodevelopmental toxicants and to characterize their transcriptome disturbances. Arch Toxicol. 2020; 94(1):151-171. doi:10.1007/s00204-019-02612-5.
  11. Tanner, E., Unenge, M., Wikstrom, S., Lindh, C., Kiviranta, H., Gennings, C., Bornehag, CG. (2020).Early Prenatal Exposure to Suspected Endocrine Disruptor Mixtures is Associated with Lower IQ at Age Seven. Env Int,