Novel testing methods for endocrine disruption linked to developmental neurotoxicity


Animation: Introduction to the ENDpoiNTs project

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Chemical pollution is affecting the brain development of future generations often implicating endocrine disruption of epigenetic processes

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Our Research

To develop an integrated platform of in vivo, in vitro and in silico methods for testing chemicals for ED properties impacting on neurodevelopment.

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Kick-off meeting ENDpoiNTs 28-29 January 2019, The Netherlands

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The European project ENDpoiNTs will develop new testing and screening methods to identify endocrine disrupting chemicals (EDCs) that induce human developmental  neurotoxicity (DNT). Clear evidence supports associations between endocrine disrupting chemical (EDC) exposure and impaired neurodevelopment. Yet, current hazard assessment of EDCs does not address developmental neurotoxicity. This is due to lack of scientific knowledge on how endocrine disruption is linked to developmental neurotoxicity (DNT). Thus there is an urgent need for novel testing and screening tools to address ED-induced DNT, based on new scientific knowledge.