Publications

Over its running period, ENDpoiNTs has produced 63 publications (see list below), whereas many more are currently under preparation. ENDpoiNTs have published the following articles:

63. Özel F, Stratmann M, Papadopoulos FC, Rüegg J, Bornehag CG. 2024. Gender-specific play behavior in relation to autistic traits and behavioral difficulties at the age of seven in the SELMA study. PLoS One, 28;19(8):e0308605. doi: 10.1371/journal.pone.0308605.

62. Marinopoulou M, Åsberg Johnels J, Bornehag CG, Unenge Hallerbäck M, Billstedt E. 2024. Do Wechsler intelligence scales predict academic achievement in children with ADHD or autism? A systematic review and meta-analysis. Appl Neuropsychol Child, 8:1-15. doi: 10.1080/21622965.2024.2361022.

61. van Melis LVJ, Peerdeman AM, Huiberts EHW, van Kleef RGDM, de Groot A, Westerink RHS. 2024. Effects of acute insecticide exposure on neuronal activity in vitro in rat cortical cultures. Neurotoxicology. 2024 May;102:58-67. doi: 10.1016/j.neuro.2024.04.004.

60. Özel, F., Rüegg, J. 2023. Exposure to endocrine-disrupting chemicals and implications for neurodevelopment. Dev. Med. Child Neurol., 65, 1005-1011. https://doi.org/10.1111/dmcn.15551

59. Symeonides, C., Vacy, K., Thomson, S., Tanner, S., Kheng Chua, H., Dixit, S., Mansell, T., O’Hely, M., Novakovic, B., Herbstman, J.B., Wang, S.,  Guo, J., Chia, J., Thao Tran, N., Eun Hwang,  S., Britt, K., Chen, F., Hwan Kim, T., Reid, C.A., El-Bitar, A., Bernasochi, G.B., Durham Delbridge, L.M., Harley, V.R., Yap, Y.W., Dewey, D., Love, C.J., Burgner, D., Tang, M.L.K., Sly, P.D., Saffery, R., Mueller, J.F., Rinehart, N., Tonge, B., Vuillermin, P., Ponsonby, A-L., Chin Boon W. 2024. Male autism spectrum disorder is linked to brain aromatase disruption by prenatal BPA in multimodal investigations and 10HDA ameliorates the related mouse phenotype. Nat. Comm., 15:6367. DOI: 10.1038/s41467-024-48897-8.

58. Caporale, N., Stucchi, S., Cheroni, C., Testa, G. 2023. Chapter 23 - Brain organoids modeling of genetic and environmental impact on neurodevelopmental traits, Editor(s): Marianne J. Legato, Dov Feldberg, Marek Glezerman. Book Sex, Gender, and Epigenetics. Academic Press, 281-290, ISBN 9780128239377, https://doi.org/10.1016/B978-0-12-823937-7.00023-7.

57. Alejandro López-Tobón, A., Shyti, R., Villa, C.E., Cheroni, C., Fuentes-Bravo, P., Trattaro, S., Caporale, N., Troglio, F., Tenderini, E., Mihailovich, M., Skaros. A., Gibson, W.T., Cuomo, A., Bonaldi, T., Mercurio, C., Varasi, M., Osborne, L., Testa, G. 2023. Science Advances, 9, DOI: 10.1126/sciadv.adh2726.

56. GTF2I dosage regulates neuronal differentiation and social behavior in 7q11.23 neurodevelopmental disorders.

55. Butruille, L., P. Jubin, E. Martin, M.S. Aigrot, M. Lhomme, J.B. Fini, B. Demeneix, B. Stankoff, C. Lubetzki, B. Zalc, S. Remaud. 2023. Deleterious functional consequences of perfluoroalkyl substances accumulation into the myelin sheath. Environ. Int. 180,108211, https://doi.org/10.1016/j.envint.2023.108211.

54. Linillos-Pradillo, B.; Paredes, S.D.; Ortiz-Cabello, M.; Schlumpf, M.; Lichtensteiger, W.; Vara, E.; Tresguerres, J.A.F.; Rancan, L. Activation of NLRP3 Inflammasome in Liver of Long Evans Lactating Rats and Its Perinatal Effects in the Offspring after Bisphenol F Exposure. Int. J. Mol. Sci. 2023, 24, 14129. https://doi.org/10.3390/ijms241814129

53. Lichtensteiger, W., C. Bassetti-Gaille, H. Rehrauer, J. Felix Escalera, B. Linillos-Pradillo, H. Idrissi, L. Miguéles-Salas, L. Rancan, S. Evangelista, M. De La Fuente, P. Leonards, S. Paredes, J. Rüegg, C.-G. Bornehag, J.A. Tresguerres, M. Schlumpf. 2023. Transcriptomics in Developing Rat Hippocampus Perinatally Exposed to Environmental Endocrine Active Chemicals and Impaired Memory Function in Adult Offspring: Convergence of Chemical Actions on Common Signalling Pathways. Toxicology Letters, 384,S132.https://doi.org/10.1016/S0378-4274(23)00568-4.

52. Evangelista S, Vazakidou P, Koekkoek J, Heinzelmann MT, Lichtensteiger W, Schlumpf M, Tresguerres JAF, Linillos-Pradillo B, van Duursen MBM, Lamoree MH, Leonards PEG. High throughput LC-MS/MS method for steroid hormone analysis in rat liver and plasma - unraveling methodological challenges. Talanta. 2023, 124981. https://doi:10.1016/j.talanta.2023.124981.

51. Chris Gennings, Katherine Svensson, Alicja Wolk, Christian Lindh, Hannu Kiviranta, Carl-Gustaf Bornehag. Using Metrics of a Mixture Effect and Nutrition from an Observational Study for Consideration towards Causal Inference. 2022.International Journal of Environmental Research and Public Health. https://doi:10.3390/ijerph19042273.

50. A. Cediel-Ulloa, R. Awoga, X. Yu, A. Gliga, A. Forsby, J. Rüegg. SOC-VI-03 Applicability of the murine neural progenitor C17.2 cell-line for assessment of developmental neurotoxicity induced by endocrine disruptors. 2022.Toxicology Letters. https://doi:10.1016/j.toxlet.2022.07.223.

49. Maria Sapounidou, Ulf Norinder, Patrik L. Andersson. Predicting Endocrine Disruption Using Conformal Prediction – A Prioritization Strategy to Identify Hazardous Chemicals with Confidence. 2023. Chemical Research in Toxicology. https://doi:10.1021/acs.chemrestox.2c00267.

48. Fatih Özel, Marlene Stratmann, Christian Lindh, Chris Gennings, Carl-Gustaf Bornehag, Joëlle Rüegg. Prenatal exposure to phthalates and gender-specific play behavior at seven years of age in the SELMA study. 2023. Environment International. https://doi:10.1016/j.envint.2023.108029.

47. Beatriz Linillos-Pradillo, Lisa Rancan, Julio García Murias, Margret Schlumpf, Walter Lichtensteiger, J. A. F. Tresguerres, Elena Vara, Sergio D. Paredes. Oxidative stress increases in liver of lactating rats after BPF-low-dose exposure: perinatal effects in the offspring. 2023. Scientific Reports. https://doi:10.1038/s41598-023-38434-w.

46. Lennart V.J. van Melis, Harm J. Heusinkveld, Celine Langendoen, Anouk Peters, Remco H.S. Westerink. Organophosphate insecticides disturb neuronal network development and function via non-AChE mediated mechanisms. 2023. NeuroToxicology. https://doi:10.1016/j.neuro.2022.11.002.

45. Nicolò Caporale, Davide Castaldi, Marco Tullio Rigoli, Cristina Cheroni, Sebastiano Trattaro, Alessia Valenti, Matteo Bonfanti, Sarah Stucchi, Alejandro Lopez Tobon, Dario Ricca, Manuel Lessi, Martina Pezzali, Alessandro Vitriolo, Katharina T. Schmid,  Matthias Heinig, Fabian J. Theis, Carlo Emanuele Villa, Giuseppe Testa. Multiplexing cortical brain organoids for the longitudinal dissection of developmental traits at single cell resolution. 2023. bioRxiv . https://doi:10.1101/2023.08.21.553507.

44. Esther Henriet, Elodie M Martin, Pauline Jubin, Dominique Langui, Abdelkrim Mannioui, Bruno Stankoff, Catherine Lubetzki, Arseny Khakhalin, Bernard Zalc. Monitoring recovery after CNS demyelination, a novel tool to de-risk pro-remyelinating strategies. 2023. Brain. https://doi:10.1093/brain/awad051.

43. Andrea Cediel-Ulloa, Ximiao Yu, Maria Hinojosa, Ylva Johansson, Anna Forsby, Karin Broberg, Joëlle Rüegg. Methylmercury-induced DNA methylation—From epidemiological observations to experimental evidence. 2022.Frontiers in Genetics. https://doi:10.3389/fgene.2022.993387.

42. M. Schlumpf, J. Félix, B. Linillos-Pradillo, H. Idrissi, L. Miguélez-Salas, L. Rancan, S.D. Paredes, M. De la Fuente, P. Leonards, J. Rüegg, J.A.F. Tresguerres, W. Lichtensteiger. LP-33 Memory Function in Adult Rat Offspring Following Perinatal Exposure to Chemicals Affecting Gene Expression Patterns in Developing Hippocampus. 2022.Toxicology Letters. 10.1016/j.toxlet.2022.07.773.

41. Beatriz Linillos-Pradillo, Lisa Rancan, Sergio D. Paredes, Margret Schlumpf, Walter Lichtensteiger, Elena Vara, Jesús Á. F. Tresguerres. Low Dose of BPA Induces Liver Injury through Oxidative Stress, Inflammation and Apoptosis in Long–Evans Lactating Rats and Its Perinatal Effect on Female PND6 Offspring. 2023. International Journal of Molecular Sciences. https://doi:10.3390/ijms24054585.

40. Maria Marinopoulou, Maria Unenge Hallerbäck, Carl-Gustaf Bornehag, Eva Billstedt. Is WISC-IV Working Memory Index associated with ADHD symptoms in 7–8-year-olds?. 2023. Applied Neuropsychology: Child. https://doi:10.1080/21622965.2023.2176232.

39. Michael Dietrich, Christina Hecker, Elodie Martin, Dominique Langui, Michael Gliem, Bruno Stankoff, Catherine Lubetzki, Joel Gruchot, Peter Göttle, Andrea Issberner, Milad Nasiri, Pamela Ramseier, Christian Beerli, Sarah Tisserand, Nicolau Beckmann, Derya Shimshek, Patrick Petzsch, David Akbar, Bodo Levkau, Holger Stark, Karl Köhrer, Hans-Peter Hartung, Patrick Küry, Sven Günther Meuth, Marc Bigaud, Bernard Zalc, Philipp Albrecht. Increased Remyelination and Proregenerative Microglia Under Siponimod Therapy in Mechanistic Models. 2022.Neurology Neuroimmunology Neuroinflammation. https://doi:10.1212/nxi.0000000000001161.

38. Nicolò Caporale, Michelle Leemans, Lina Birgersson, Pierre-Luc Germain, Cristina Cheroni, Gábor Borbély, Elin Engdahl, Christian Lindh, Raul Bardini Bressan, Francesca Cavallo, Nadav Even Chorev, Giuseppe Alessandro D’agostino, Steven M. Pollard, Marco Tullio Rigoli, Erika Tenderini, Alejandro Lopez Tobon, Sebastiano Trattaro, Flavia Troglio, Matteo Zanella, Åke Bergman, Pauliina Damdimopoulou, Maria Jönsson, Wieland Kiess, Efthymia Kitraki, Hannu Kiviranta, Eewa Nånberg, Mattias Öberg, Panu Rantakokko, Christina Rudén, Olle Söder, Carl-Gustaf Bornehag, Barbara Demeneix, Jean-Baptiste Fini, Chris Gennings, Joëlle Rüegg, Joachim Sturve, Giuseppe Testa. From cohorts to molecules: Adverse impacts of endocrine disrupting mixtures. 2022.Science. https://doi:10.1126/science.abe8244.

37. Maria Sapounidou,Patrik L. Andersson ,Michelle Leemans, Jean-Baptiste Fini, Barbara Demeneix, Joëlle Rüegg, Carl-Gustaf Bornehag, Chris Gennings. From Cohort to Cohort: A Similar Mixture Approach (SMACH) to Evaluate Exposures to a Mixture Leading to Thyroid-Mediated Neurodevelopmental Effects Using NHANES Data. 2023. Toxics. https://doi:10.3390/toxics11040331.

36. Andrea Cediel-Ulloa, Sabrina Lindner, Joëlle Rüegg, Karin Broberg. Epigenetics of methylmercury. 2023. NeuroToxicology. https://doi:10.1016/j.neuro.2023.05.004.

35. Diana-Ioana Lupu, Andrea Cediel Ulloa, Joëlle Rüegg. Endocrine Disrupting Chemicals and Hippocampal Development: The Role of Estrogen and Androgen Signalling. 2023. Neuroendocrinology. https://doi:10.1159/000531669.

34. W. Lichtensteiger, C. Bassetti-Gaille, H. Rehrauer, J. Félix, B. Linillos-Pradillo, H. Idrissi, L. Miguélez-Salas, L. Rancan, S.D. Paredes, M. De la Fuente, P. Leonards, J. Rüegg, J.A.F. Tresguerres, M. Schlumpf. LP-32 Comparative Transcriptomics in Developing Rat Hippocampus After Perinatal Exposure to Bisphenol F (BPF), Butylbenzylphthalate (BBzP), 1,2-Cyclohexane dicarboxylic acid diisononyl ester (DINCH), Permethrin (PMT), Perfluorooctanesulfonic acid (PFOS), and Triphenylphosphate (TPHP). 2022.Toxicology Letters. https://doi:10.1016/j.toxlet.2022.07.772.

33. Arash Derakhshan, Andreas Kortenkamp, Huan Shu, Maarten A C Broeren, Christian H Lindh, Robin P Peeters, Carl-Gustaf Bornehag, Barbara Demeneix, Tim I M Korevaar. Association of per- and polyfluoroalkyl substances with thyroid homeostasis during pregnancy in the SELMA study. 2022.Environment International. https://doi:10.1016/j.envint.2022.107420.

32. Maria Marinopoulou, Eva Billstedt, Catrin Wessman, Carl-Gustaf Bornehag, Maria Unenge Hallerbäck. Association Between Intellectual Functioning and Autistic Traits in the General Population of Children. 2023. Child Psychiatry and Human Development. https://doi:10.1007/s10578-023-01562-5.

31. Michela Di Criscio, Jennifer Ekholm Lodahl, Antonios Stamatakis, Efthymia Kitraki, Ioannis Bakoyiannis, Anastasia Repouskou, Carl-Gustaf Bornehag, Chris Gennings, Diana Lupu, Joëlle Rüegg. A human-relevant mixture of endocrine disrupting chemicals induces changes in hippocampal DNA methylation correlating with hyperactive behavior in male mice. 2023. Chemosphere. https://doi:10.1016/j.chemosphere.2022.137633.

30. Cediel-Ulloa, Andrea; Diana Loana Lupu; Ylva Johansson; Maria Hinojosa; Fatih Özel; Joëlle Rüegg. 2022. Impact of endocrine disrupting chemicals on neurodevelopment: the need for better testing strategies for endocrine disruption-induced developmental neurotoxicity. Expert Review of Endocrinology & Metabolism, 17:2, 131-141, https://doi:10.1080/17446651.2022.2044788.

29. Klose, Jördis; Julia Tigges; Stefan Masjosthusmann; Katharina Schmuck; Farina Bendt; Ulrike Hübenthal; Patrick Petzsch; Karl Köhrer; Katharina Koch; Ellen Fritsche. 2021. TBBPA targets converging key events of human oligodendrocyte development resulting in two novel AOPs. ALTEX. https://doi:10.14573/altex.2007201.

28. Marangon, Davide; Nicolò Caporale; Marta Boccazzi; Maria P. Abbracchio; Giuseppe Testa; Davide Lecca. 2021. Novel in vitro Experimental Approaches to Study Myelination and Remyelination in the Central Nervous System.Frontiers in cellular neuroscience. https://doi:10.3389/fncel.2021.748849.

27. Gerber, Lora-Sophie; Lennart V J van Melis; Regina G D M van Kleef; Aart de Groot; Remco H S Westerink. 2021. Culture of Rat Primary Cortical Cells for Microelectrode Array (MEA) Recordings to Screen for Acute and Developmental Neurotoxicity.Curr Protoc . https://doi:e158.10.1002/cpz1.158.

26. Engdahl, Elin; Katherine Svensson; Ping-I Daniel Lin; Ali Alavian-Ghavaninic; Christian Lindh; Joëlle Rüegg; Carl-Gustaf Bornehag. 2021. DNA methylation at GRIN2B partially mediates the association between prenatal bisphenol F exposure and cognitive functions in 7-year-old children in the SELMA study. Environment International. https://doi:106617.10.1016/j.envint.2021.106617.

25. Audouze, Karine; Elias Zgheib; Khaled Abass; Asma H. Baig; Isabel Forner-Piquer; Henrik Holbech; Dries Knapen; Pim E. G. Leonards; Diana I. Lupu; Saranya Palaniswamy; Arja Rautio; Maria Sapounidou; Olwenn V. Martin. 2021. Evidenced-Based Approaches to Support the Development of Endocrine-Mediated Adverse Outcome Pathways: Challenges and Opportunities. Toxicol. https://doi:10.3389/ftox.2021.787017.

24. Demeneix, Barbara A. 2021. Environmental influences on brain aging.Aging Brain. https://doi:100003.10.1016/j.nbas.2020.100003.

23. Delp , J , Cediel-Ulloa , A , Suciu , I , Kranaster , P , van Vugt-Lussenburg , B M , Munic Kos , V , van der Stel , W , Carta , G , Bennekou , S H , Jennings , P , van de Water , B , Forsby , A & Leist , M. 2021. Neurotoxicity and underlying cellular changes of 21 mitochondrial respiratory chain inhibitors, Archives of Toxicology , vol. 95 , pp. 591–615 . https://doi:10.1007/s00204-020-02970-5.10.1007/s00204-020-02970-5.

22. Loser, Dominik; Dominik Loser; Karin Grillberger; Maria G. Hinojosa; Jonathan Blum; Yves Haufe; Timm Danker; Ylva Johansson; Clemens Möller; Annette Nicke; Susanne Hougaard Bennekou; Iain Gardner; Caroline Bauch; Paul Walker; Anna Forsby; Gerhard F. Ecker; Udo Kraushaar; Marcel Leist. 2021. Acute effects of the imidacloprid metabolite desnitro-imidacloprid on human nACh receptors relevant for neuronal signaling. Archives of Toxicology. https://doi:10.1007/s00204-021-03168-z.

21. Klima, Stefanie; Markus Brüll; Anna-Sophie Spreng; Ilinca Suciu; Tjalda Falt; Jens Christian Schwamborn; Tanja Waldmann; Christiaan Karreman; Marcel Leist. 2021. A human stem cell-derived test system for agents modifying neuronal N -methyl- d -aspartate-type glutamate receptor Ca 2+ -signalling.Archives of Toxicology. https://doi:10.1007/s00204-021-03024-0.

20. Loser, Dominik; Maria G. Hinojosa; Jonathan Blum; Jasmin Schaefer; Markus Brüll; Ylva Johansson; Ilinca Suciu; Karin Grillberger; Timm Danker; Clemens Möller; Iain Gardner; Gerhard F. Ecker; Susanne Hougaard Bennekou; Anna Forsby; Udo Kraushaar; Marcel Leist. 2021. Functional alterations by a subgroup of neonicotinoid pesticides in human dopaminergic neurons. Archives of Toxicology. https://doi:10.1007/s00204-021-03031-1.

19. Dolde, Xenia; Christiaan Karreman; Marianne Wiechers; Stefan Schildknecht; Marcel Leist. 2021. Profiling of Human Neural Crest Chemoattractant Activity as a Replacement of Fetal Bovine Serum for In Vitro Chemotaxis Assays.International Journal of Molecular Sciences. https://doi:10.3390/ijms221810079.

18. Kappenberg, Franziska; Tim Brecklinghaus; Wiebke Albrecht; Jonathan Blum; Carola van der Wurp; Marcel Leist; Jan G. Hengstler; Jörg Rahnenführer. 2020. Handling deviating control values in concentration-response curves..Archives of Toxicology. https://doi:10.1007/s00204-020-02913-0.

17. Meisig, Johannes; Johannes Meisig; Nadine Dreser; Marion Kapitza; Margit Henry; Tamara Rotshteyn; Jörg Rahnenführer; Jan G. Hengstler; Agapios Sachinidis; Tanja Waldmann; Marcel Leist; Nils Blüthgen; Nils Blüthgen. 2020. Kinetic modeling of stem cell transcriptome dynamics to identify regulatory modules of normal and disturbed neuroectodermal differentiation. Nucleic Acids Research. https://doi:10.1093/nar/gkaa1089.

16. López-Tobón, Alejandro; Alejandro López-Tobón; Sebastiano Trattaro; Sebastiano Trattaro; Giuseppe Testa; Giuseppe Testa. 2020. The sociability spectrum: evidence from reciprocal genetic copy number variations..Molecular Autism. https://doi:10.1186/s13229-020-00347-0.

15. Loser, Dominik; Jasmin Schaefer; Timm Danker; Clemens Möller; Markus Brüll; Ilinca Suciu; Anna-Katharina Ückert; Stefanie Klima; Marcel Leist; Udo Kraushaar. 2020 .Human neuronal signaling and communication assays to assess functional neurotoxicity. Archives of Toxicology. https://doi:10.1007/s00204-020-02956-3.

14. Snaidero, Nicolas; Martina Schifferer; Aleksandra Mezydlo; Bernard Zalc; Martin Kerschensteiner; Thomas Misgeld; Thomas Misgeld. 2020. Myelin replacement triggered by single-cell demyelination in mouse cortex..Nature Communications. https://doi:10.1038/s41467-020-18632-0.

13. Cheroni, Cristina; Cristina Cheroni; Nicolò Caporale; Nicolò Caporale; Giuseppe Testa; Giuseppe Testa.2020. Autism spectrum disorder at the crossroad between genes and environment: contributions, convergences, and interactions in ASD developmental pathophysiology.Molecular Autism. https://doi:10.1186/s13229-020-00370-1.

12. Tanner, E., Unenge, M., Wikstrom, S., Lindh, C., Kiviranta, H., Gennings, C., Bornehag, CG. (2020).Early Prenatal Exposure to Suspected Endocrine Disruptor Mixtures is Associated with Lower IQ at Age Seven. Env Int, https://doi.org/10.1016/j.envint.2019.105185

11. Dreser N, Madjar K, Holzer AK, et al. Development of a neural rosette formation assay (RoFA) to identify neurodevelopmental toxicants and to characterize their transcriptome disturbances. Arch Toxicol. 2020; 94(1):151-171. https://doi:10.1007/s00204-019-02612-5.

10. Brüll, M., Spreng, A.-S., Gutbier, S., Loser, D., Krebs, A., Reich, M., Kraushaar, U., Britschgi, M., Patsch, C. and Leist, M. Incorporation of stem cell-derived astrocytes into neuronal organoids to allow neuro-glial interactions in toxicological studies. ALTEX - Alternatives to animal experimentation, 2020; 37(3), pp. 409-428. https://doi:10.14573/altex.1911111.

9. Karreman, C., Klima, S., Holzer, A.-K. and Leist, M. CaFFEE: A program for evaluating time courses of Ca2+ dependent signal changes of complex cells loaded with fluorescent indicator dyes. ALTEX - Alternatives to animal experimentation, 2020; 37(2), pp. 332-336. https://doi:10.14573/altex.2003191.

8. Troger, F.; Johannes Delp; Melina Funke; Wanda van der Stel; Claire Colas; Marcel Leist; Bob van de Water; Gerhard F. Ecker. Identification of mitochondrial toxicants by combined in silico and in vitro studies : a structure-based view on the Adverse Outcome Pathway. 2020. Computational Toxicology, 14. https://doi:10.1016/j.comtox.2020.100123.

7. Krebs, A., Nyffeler, J., Karreman, C., Schmidt, B. Z., Kappenberg, F., Mellert, J., Pallocca, G., Pastor, M., Rahnenführer, J. and Leist, M. Determination of benchmark concentrations and their statistical uncertainty for cytotoxicity test data and functional in vitro assays. ALTEX - Alternatives to animal experimentation, 2020; 37(1), pp. 155-163. https://doi:10.14573/altex.1912021.

6. Karreman, C., Kranaster, P. and Leist, M. SUIKER: Quantification of antigens in cell organelles, neurites and cellular sub-structures by imaging. ALTEX - Alternatives to animal experimentation, 2019; 36(3), pp. 518-520. doi: 10.14573/altex.1906251.

5. Krebs A, Waldmann T, Wilks MF, Van Vugt-Lussenburg BMA, Van der Burg B, Terron A, Steger-Hartmann T, Ruegg J, Rovida C, Pedersen E, Pallocca G, Luijten M, Leite SB, Kustermann S, Kamp H, Hoeng J, Hewitt P, Herzler M, Hengstler JG, Heinonen T, Hartung T, Hardy B, Gantner F, Fritsche E, Fant K, Ezendam J, Exner T, Dunkern T, Dietrich DR, Coecke S, Busquet F, Braeuning A, Bondarenko O, Bennekou SH, Beilmann M, Leist M. Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data. ALTEX - Alternatives to animal experimentation, 2019;36(4):682-699. https://doi:10.14573/altex.1909271.

4. Demeneix BA. Evidence for Prenatal Exposure to Thyroid Disruptors and Adverse Effects on Brain Development. Eur Thyroid J. 2019;8(6):283-292. https://doi:10.1159/000504668.

3. López-Tobón A, Emanuele Villa C, Cheroni C. et al. Human Cortical Organoids Expose a Differential Function of GSK3 on Cortical Neurogenesis. Stem Cell Reports. 2019; 13(5):847-861. https://doi.org/10.1016/j.stemcr.2019.09.005.

2. Leemans M, Couderq S, Demeneix B, Fini JB. Pesticides With Potential Thyroid Hormone-Disrupting Effects: A Review of Recent Data. Front Endocrinol (Lausanne). 2019;10:743. https://doi:10.3389/fendo.2019.00743.

1. Lupu D, Andersson P, Bornehag CG, et al. The ENDpoiNTs Project: Novel Testing Strategies for Endocrine Disruptors Linked to Developmental Neurotoxicity. Int J Mol Sci. 2020;21(11):3978. https://doi:10.3390/ijms21113978.